CONNEXIN DOMAINS RELEVANT TO THE CHEMICAL GATING OF GAP JUNCTION CHANNELS




A nonhuman primate model of vertical sleeve gastrectomy facilitates mechanistic and translational research in human obesity

Summary: The obesity epidemic significantly contributes to overall morbidity and mortality.Bariatric surgery is the gold standard treatment for obesity and metabolic dysfunction, yet the mechanisms by which it exerts metabolic benefit remain unclear.Here, we demonstrate a model of vertical sleeve gastrectomy (VSG) in nonhuman primates (NHP) that mi

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